Acute Promyelocytic Leukaemia(APML) in an Adult Patient Presenting with Multiple Lytic Bony Lesions – The First of its Kind – A Case Report with Review of Literature

Oncology, Gastroenterology and Hepatology Reports,2017,6,2,80-82.
Published:February 2017
Type:Case Report
Author(s) affiliations:

Rajeev Lakkavalli Krishnappa, Govinda Babu Kanakasetty, Suresh Babu Mallekavu Chikkadasappa, Suparna Ajit Rao*

Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bangalore, Karnataka, INDIA.


Acute promyelocytic leukaemia presenting with bony lesions alongside medullary involvement is rare with anecdotal reports having noted this manifestation in a newly diagnosed case. We here report an infrequent presentation of a young adult male presenting solely with multiple axial and pelvic bone lesions initially, with the initial impression being a lymphoma /infiltrative lesion. This is a case report that reiterates the need for prompt diagnosis and a thorough evaluation for early treatment, especially since this is a curable malignancy.

Pretreatment FDG- PET/CT imaging suggestive of vertebral lesion