Cancer of the stomach usually presents with fullness, decreased appetite, malena or hematemesis. Unusual presentations include distant metastasis as a primary presentation, rectal tumor, cutaneous metastasis and others. Stomach cancer presenting as portal vein thrombosis (PVT) has not been reported previously. We here present an adult female who presented to us with symptoms suggestive of PVT and was found to have cancer of the stomach. A brief review of the literature follows.