Synchronous Primary Adenocarcinoma and Gastrointestinal Stromal Tumor of Stomach: A Case Report and Review of Literature

Oncology, Gastroenterology and Hepatology Reports,2014,3,1,1-3.
Published:January 2014
Type:Case Report
Author(s) affiliations:

Rumana Makhdoomi, Rais Malik, Gull Mohammad1, Nuzhat Samoon, Mohsin Rasool, Humaira Bashir, Shazia Bashir, K. M. Baba, Alam Khursheed2

Departments of Pathology, 1Oncology and 2Surgery, Sher‑i‑Kashmir Institute Medical Sciences, Street Soura Srinagar, Kashmir, India


A synchronous occurrence of epithelial and gastrointestinal stromal tumors (GISTs) in the stomach is unusual. The association has often been detected incidentally and it is not known whether such an association is a simple incidental coexistence or there is a causal relationship between the two lesions. We hereby report a 70‑year‑old male operated for adenocarcinoma of stomach who, besides the primary lesion in the lesser curve, had another lesion i.e., GIST on the serosal aspect of antrum picked up on gross examination of the specimen. The tumor was GIST of low risk category which was positive for tumor markers CD117 (C‑kit) and CD34. The case is presented here for its rarity.