Infantile hepatic hemangioendothelioma presenting as early heart failure: An autopsy case report

Oncology, Gastroenterology and Hepatology Reports,2015,4,1,43-45.
Published:January 2015
Type:Case Report
Authors:
Author(s) affiliations:

Richa D. Patel, Manisha Khare, Nikhil Majethia, Alka Kalgutkar

Department of Pathology, Lokmanya Tilak Municipal Medical College and Hospital, Sion, Mumbai, Maharashtra, India

Abstract:

Infantile hepatic hemangioendothelioma (IHHE) is the most common type of hepatic vascular tumor in infancy, but is rarely reported because of the low incidence estimated to be about 1/20,000. We report an autopsy case of IHHE in a 20‑day‑old female who came with an initial manifestation of abdominal distension and congestive heart failure (CHF). Symptoms of cardiac decompensation gradually worsened in spite of treatment and child died within 2 days. On autopsy, grossly enlarged liver showed microscopy of large ecstatic vascular channels lined by single layer of plump endothelial cells and diagnosis was given as Type I IHHE. CHF is common complication due to arteriovenous shunts within the tumor and contributes to high morbidity and mortality in up to 70% of untreated infants with median age of presentation of 1‑month. Therefore, if symptoms develop, aggressive treatments are warranted.